The quest for targets executing MYC-dependent cell transformation

MYC represents a transcription factor with oncogenic potential converting multiple cellular signals into a broad transcriptional response, thereby controlling the expression of numerous protein-coding and non-coding RNAs important for cell proliferation, metabolism, differentiation, and apoptosis. C...

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Bibliographic Details
Main Author: Markus eHartl
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-06-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2016.00132/full