Delayed and highly specific antibody response to nonstructural protein 1 (NS1) revealed during natural human ZIKV infection by NS1-based capture ELISA

Delayed and highly specific antibody response to nonstructural protein 1 (NS1) revealed during natural human ZIKV infection by NS1-based capture ELISA

Abstract Background Zika virus (ZIKV) had spread rapidly in the past few years in southern hemisphere where dengue virus (DENV) had caused epidemic problems for over half a century. The high degree of cross-reactivity of Envelope (E) protein specific antibody responses between ZIKV and DENV made it...

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Bibliographic Details
Main Authors: Xiujie Gao, Yingfen Wen, Jian Wang, Wenxin Hong, Chunlin Li, Lingzhai Zhao, Chibiao Yin, Xia Jin, Fuchun Zhang, Lei Yu
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Infectious Diseases
Subjects:
Zika virus
Dengue virus
Non-structural protein 1
Antibody response
Cross-reactivity
Online Access:http://link.springer.com/article/10.1186/s12879-018-3173-y

Internet

http://link.springer.com/article/10.1186/s12879-018-3173-y

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