How Many Drugs Are Catecholics

By examination of the 8659 drugs recorded in the Comprehensive Medicinal Chemistry (CMC) database, 78 catecholics (including five pyrogallolics) were identified, of which 17 are currently prescribed by FDA. Through analyzing the substitutent patterns, ClogPs and O-H bond dissociation enthalpies(BDEs...

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Bibliographic Details
Main Authors: Da-Peng Yang, Hong-Fang Ji, Guang-Yan Tang, Wei Ren, Hong-Yu Zhang
Format: Article
Language:English
Published: MDPI AG 2007-04-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/12/4/878/