Chronic nicotine modifies skeletal muscle Na,K-ATPase activity through its interaction with the nicotinic acetylcholine receptor and phospholemman.

Chronic nicotine modifies skeletal muscle Na,K-ATPase activity through its interaction with the nicotinic acetylcholine receptor and phospholemman.

Our previous finding that the muscle nicotinic acetylcholine receptor (nAChR) and the Na,K-ATPase interact as a regulatory complex to modulate Na,K-ATPase activity suggested that chronic, circulating nicotine may alter this interaction, with long-term changes in the membrane potential. To test this...

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Bibliographic Details
Main Authors: Alexander V Chibalin, Judith A Heiny, Boubacar Benziane, Alexander V Prokofiev, Alexander V Vasiliev, Violetta V Kravtsova, Igor I Krivoi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3307752?pdf=render

Internet

http://europepmc.org/articles/PMC3307752?pdf=render

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