Oral Beta-Lactamase Protects the Canine Gut Microbiome from Oral Amoxicillin-Mediated Damage

Antibiotics damage the gut microbiome, which can result in overgrowth of pathogenic microorganisms and emergence of antibiotic resistance. Inactivation of antibiotics in the small intestine represents a novel strategy to protect the colonic microbiota. SYN-004 (ribaxamase) is a beta-lactamase formul...

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Bibliographic Details
Main Authors: Sheila Connelly, Brian Fanelli, Nur A. Hasan, Rita R. Colwell, Michael Kaleko
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Microorganisms
Subjects:
Online Access:https://www.mdpi.com/2076-2607/7/5/150