Targeting TBP-associated factors in ovarian cancer

As ovarian tumors progress, they undergo a process of dedifferentiation, allowing adaptive changes in growth and morphology that promote metastasis and chemoresistance. Herein, we outline a hypothesis that TATA-box binding protein (TBP) associated factors (TAFs), which compose the RNA Polymerase II...

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Bibliographic Details
Main Authors: Jennifer R Ribeiro, Lindsay A Lovasco, Barbara C Vanderhyden, Richard N Freiman
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00045/full