Identifying genetic variants that affect viability in large cohorts.
A number of open questions in human evolutionary genetics would become tractable if we were able to directly measure evolutionary fitness. As a step towards this goal, we developed a method to examine whether individual genetic variants, or sets of genetic variants, currently influence viability. Th...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-09-01
|
Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC5584811?pdf=render |