Prevention of Infections in Cardiac Surgery study (PICS): study protocol for a pragmatic cluster-randomized factorial crossover pilot trial

Prevention of Infections in Cardiac Surgery study (PICS): study protocol for a pragmatic cluster-randomized factorial crossover pilot trial

Abstract Background A wide range of prophylactic antibiotic regimens are used for patients undergoing open-heart cardiac surgery. This reflects clinical equipoise in choice and duration of antibiotic agents. Although individual-level randomized control trials (RCT) are considered the gold standard w...

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Bibliographic Details
Main Authors: Rachel B. van Oostveen, Alberto Romero-Palacios, Richard Whitlock, Shun Fu Lee, Stuart Connolly, Alex Carignan, C. David Mazer, Mark Loeb, Dominik Mertz
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Trials
Subjects:
antibiotic prophylaxis
cardiac surgery
cluster crossover trial
Online Access:http://link.springer.com/article/10.1186/s13063-018-3080-y

Internet

http://link.springer.com/article/10.1186/s13063-018-3080-y

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