Effects of PUMILIO1 and PUMILIO2 knockdown on cardiomyogenic differentiation of human embryonic stem cells culture.

Effects of PUMILIO1 and PUMILIO2 knockdown on cardiomyogenic differentiation of human embryonic stem cells culture.

Posttranscriptional regulation plays a fundamental role in the biology of embryonic stem cells (ESCs). Many studies have demonstrated that multiple mRNAs are coregulated by one or more RNA-binding proteins (RBPs) that orchestrate mRNA expression. A family of RBPs, which is known as the Pumilio-FBF (...

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Bibliographic Details
Main Authors: Isabelle Leticia Zaboroski Silva, Anny Waloski Robert, Guillermo Cabrera Cabo, Lucia Spangenberg, Marco Augusto Stimamiglio, Bruno Dallagiovanna, Daniela Fiori Gradia, Patrícia Shigunov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0222373

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https://doi.org/10.1371/journal.pone.0222373

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