Noradrenergic Source of Dopamine Assessed by Microdialysis in the Medial Prefrontal Cortex

Noradrenergic Source of Dopamine Assessed by Microdialysis in the Medial Prefrontal Cortex

Previous results indicate that dopamine (DA) release in the medial prefrontal cortex (mPFC) is modified by α2 adrenoceptor- but not D2 DA receptor- agonists and antagonists, suggesting that DA measured by microdialysis in the mPFC originates from noradrenergic terminals. Accordingly, noradrenergic d...

Full description

Bibliographic Details
Main Authors: Paola Devoto, Claudia Sagheddu, Michele Santoni, Giovanna Flore, Pierluigi Saba, Marco Pistis, Gian Luigi Gessa
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Pharmacology
Subjects:
dopamine-norepinephrine interaction
noradrenergic denervation
norepinephrine transporter
D2 receptor drug
neuronal activity
ventral tegmental area
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.588160/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.588160/full

Similar Items