Genome-wide mapping of DNA strand breaks.

Determination of cellular DNA damage has so far been limited to global assessment of genome integrity whereas nucleotide-level mapping has been restricted to specific loci by the use of specific primers. Therefore, only limited DNA sequences can be studied and novel regions of genomic instability ca...

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Bibliographic Details
Main Authors: Frédéric Leduc, David Faucher, Geneviève Bikond Nkoma, Marie-Chantal Grégoire, Mélina Arguin, Raymund J Wellinger, Guylain Boissonneault
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3045442?pdf=render