Mechanisms of FSH- and Amphiregulin-Induced MAP Kinase 3/1 Activation in Pig Cumulus-Oocyte Complexes During Maturation In Vitro

Mechanisms of FSH- and Amphiregulin-Induced MAP Kinase 3/1 Activation in Pig Cumulus-Oocyte Complexes During Maturation In Vitro

The maturation of mammalian oocytes in vitro can be stimulated by gonadotropins (follicle-stimulating hormone, FSH) or their intrafollicular mediator, epidermal growth factor (EGF)-like peptide—amphiregulin (AREG). We have shown previously that in pig cumulus-oocyte complexes (COCs), FSH i...

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Bibliographic Details
Main Authors: Radek Prochazka, Lucie Nemcova
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
amphiregulin
cumulus cells
epidermal growth factor receptor
FSH
mitogen-activated protein kinase 3/1
signal transduction
Online Access:http://www.mdpi.com/1422-0067/20/5/1179

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http://www.mdpi.com/1422-0067/20/5/1179

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