KDM6B Elicits Cell Apoptosis by Promoting Nuclear Translocation of FOXO1 in Non-Small Cell Lung Cancer

KDM6B Elicits Cell Apoptosis by Promoting Nuclear Translocation of FOXO1 in Non-Small Cell Lung Cancer

Background/Aims: Non-small cell lung carcinoma (NSCLC) is the most common type of lung cancer and the cause of most cancer-related deaths. The molecular mechanisms that are involved in NSCLC development are currently not well understood. Accumulating evidence shows that histone demethylases play imp...

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Bibliographic Details
Main Authors: Jun Ma, Ning Wang, Yurong Zhang, Cun Wang, Tianxiang Ge, Haojie Jin, Xuan Deng, Xisong Huo, Dishui Gu, Zhouhong Ge, Wei Chu, Liyan Jiang, Wenxin Qin
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Metastasis
KDM6B
Nonsmall cell lung cancer
Apoptosis
FOXO1
Online Access:http://www.karger.com/Article/FullText/430345

Internet

http://www.karger.com/Article/FullText/430345

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