The application of shotgun metagenomics to the diagnosis of granulomatous amoebic encephalitis due to Balamuthia mandrillaris: a case report

The application of shotgun metagenomics to the diagnosis of granulomatous amoebic encephalitis due to Balamuthia mandrillaris: a case report

Abstract Background Granulomatous amoebic encephalitis (GAE) is an infrequent and fatal infectious disease worldwide. Antemortem diagnosis in this condition is very difficult because clinical manifestations and neuroimaging are nonspecific. Case presentation A 60-year-old Japanese woman was admitted...

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Bibliographic Details
Main Authors: Shota Hirakata, Yusuke Sakiyama, Akiko Yoshimura, Mei Ikeda, Katsunori Takahata, Yuichi Tashiro, Michiyoshi Yoshimura, Hitoshi Arata, Hajime Yonezawa, Mari Kirishima, Michiyo Higashi, Miho Hatanaka, Takuro Kanekura, Kenji Yagita, Eiji Matsuura, Hiroshi Takashima
Format: Article
Language:English
Published: BMC 2021-10-01
Series:BMC Neurology
Subjects:
Granulomatous amoebic encephalitis
Balamuthia mandrillaris infection
Necrotizing encephalitis
Next-generation sequencer
Shotgun metagenomics
Online Access:https://doi.org/10.1186/s12883-021-02418-y

Internet

https://doi.org/10.1186/s12883-021-02418-y

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