STABILITY-INDICATING METHOD FOR DETERMINATION OF TIZANIDINE HYDROCHLORIDE IN PHARMACEUTICAL LC-CAD METHOD USING CHEMOMETRIC APPROACH

STABILITY-INDICATING METHOD FOR DETERMINATION OF TIZANIDINE HYDROCHLORIDE IN PHARMACEUTICAL LC-CAD METHOD USING CHEMOMETRIC APPROACH

A new LC method for tizanidine hydrochloride in tablet dosage form using a charged aerosol detector (CAD) is described. The influence of various parameters on chromatographic system was investigated by factorial designs and Derringer's desirability. Chromatographic conditions were: mobile phase...

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Bibliographic Details
Main Authors: Mariana Brandalise, Pamela Cristina Lukasewicz Ferreira, Andrea Garcia Pereira, Leonardo Meneghini, Pedro Eduardo Fröehlich, Ana Maria Bergold
Format: Article
Language:English
Published: Universidade Federal do Rio Grande do Sul 2017-08-01
Series:Drug Analytical Research
Subjects:
tizanidine hydrochloride
cad detector
chemometrics
stability
Online Access:https://seer.ufrgs.br/dar/article/view/75607/43430

Internet

https://seer.ufrgs.br/dar/article/view/75607/43430

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