Combination erlotinib-cisplatin and Atg3-mediated autophagy in erlotinib resistant lung cancer.

Tyrosine kinase inhibitors such as erlotinib are commonly used as a therapeutic agent against cancer due to its relatively low side-effect profile and, at times, greater efficacy. However, erlotinib resistance (ER) in non-small cell lung cancer is being recognized as a major problem. Therefore, unde...

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Bibliographic Details
Main Authors: Jasmine G Lee, Reen Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23119048/?tool=EBI