Antinociceptive tolerance to NSAIDs in the anterior cingulate cortex is mediated via endogenous opioid mechanism

Antinociceptive tolerance to NSAIDs in the anterior cingulate cortex is mediated via endogenous opioid mechanism

Abstract Background In the past decade several studies have reported that in some brain areas, particularly, in the midbrain periaqueductal gray matter, rostral ventro-medial medulla, central nucleus of amygdala, nucleus raphe magnus, and dorsal hippocampus, microinjections of non-steroidal anti-inf...

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Bibliographic Details
Main Authors: Nana Tsiklauri, Natia Pirkulashvili, Ivliane Nozadze, Marina Nebieridze, Gulnaz Gurtskaia, Elene Abzianidze, Merab G. Tsagareli
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Pharmacology and Toxicology
Subjects:
Antinociception
Endogenous opioids
Descending modulation
Nociception
Non-opioid tolerance
Online Access:http://link.springer.com/article/10.1186/s40360-017-0193-y

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http://link.springer.com/article/10.1186/s40360-017-0193-y

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