Multiple antigen-engineered DC vaccines with or without IFNα to promote antitumor immunity in melanoma

Multiple antigen-engineered DC vaccines with or without IFNα to promote antitumor immunity in melanoma

Abstract Background Cancer vaccines are designed to promote systemic antitumor immunity and tumor eradication. Cancer vaccination may be more efficacious in combination with additional interventions that may build on or amplify their effects. Methods Based on our previous clinical and in vitro studi...

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Bibliographic Details
Main Authors: Lisa H. Butterfield, Lazar Vujanovic, Patricia M. Santos, Deena M. Maurer, Andrea Gambotto, Joel Lohr, Chunlei Li, Jacob Waldman, Uma Chandran, Yan Lin, Huang Lin, Hussein A. Tawbi, Ahmad A. Tarhini, John M. Kirkwood
Format: Article
Language:English
Published: BMJ Publishing Group 2019-04-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Cancer vaccine
Immune biomarkers
Tumor immunity
Shared antigens
Melanoma
Online Access:http://link.springer.com/article/10.1186/s40425-019-0552-x

Internet

http://link.springer.com/article/10.1186/s40425-019-0552-x

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