Specific Expression of a New Bruton Tyrosine Kinase Isoform (p65BTK) in the Glioblastoma Gemistocytic Histotype

Specific Expression of a New Bruton Tyrosine Kinase Isoform (p65BTK) in the Glioblastoma Gemistocytic Histotype

Bruton’s tyrosine-kinase (BTK) is a non-receptor tyrosine kinase recently associated with glioma tumorigenesis and a novel prognostic marker for poor survival in patients with glioma. The p65BTK is a novel BTK isoform involved in different pathways of drug resistance of solid tumors, thus we aimed t...

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Bibliographic Details
Main Authors: Luca Sala, Giovanni Cirillo, Gabriele Riva, Gabriele Romano, Carlo Giussani, Annamaria Cialdella, Antonio Todisco, Assunta Virtuoso, Maria Grazia Cerrito, Angela Bentivegna, Emanuela Grassilli, Antonio Ardizzoia, Emanuela Bonoldi, Roberto Giovannoni, Michele Papa, Marialuisa Lavitrano
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Bruton’s tyrosine kinase
p65BTK
gemistocytes
glioblastoma
biomarker
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00002/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2019.00002/full

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