Alteration in the Expression of Cytochrome P450s (CYP1A1, CYP2E1, and CYP3A11) in the Liver of Mouse Induced by Microcystin-LR

Microcystins (MCs) are cyclic heptapeptide toxins and can accumulate in the liver. Cytochrome P450s (CYPs) play an important role in the biotransformation of endogenous substances and xenobiotics in animals. It is unclear if the CYPs are affected by MCs exposure. The objective of this study was to e...

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Bibliographic Details
Main Authors: Bangjun Zhang, Yang Liu, Xiaoyu Li
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/7/4/1102