Diagnostic Performances of Urinary Methylmalonic Acid/Creatinine Ratio in Vitamin B12 Deficiency

Diagnostic Performances of Urinary Methylmalonic Acid/Creatinine Ratio in Vitamin B12 Deficiency

Sole measurement of plasma vitamin B12 is no longer enough to identify vitamin B12 (B12) deficiency. When plasma vitamin B12 is in the low-normal range, especially between 201 and 350 ng/L, B12 deficiency should be assessed by measurements of plasma homocysteine and/or plasma methylmalonic acid (MMA...

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Bibliographic Details
Main Authors: Sopak Supakul, Floris Chabrun, Steve Genebrier, Maximilien N’Guyen, Guillaume Valarche, Arthur Derieppe, Adeline Villoteau, Valentin Lacombe, Geoffrey Urbanski
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Journal of Clinical Medicine
Subjects:
vitamin B12 deficiency
plasma homocysteine
plasma methylmalonic acid
urinary methylmalonic acid
biomarker
renal impairment
Online Access:https://www.mdpi.com/2077-0383/9/8/2335

Internet

https://www.mdpi.com/2077-0383/9/8/2335

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