A procedure for the preparation and isolation of nucleoside-5’-diphosphates

A procedure for the preparation and isolation of nucleoside-5’-diphosphates

Tris[bis(triphenylphosphoranylidene)ammonium] pyrophosphate (PPN pyrophosphate) was used in the SN2 displacements of the tosylate ion from 5’-tosylnucleosides to afford nucleoside-5’-diphosphates. Selective precipitation permitted the direct isolation of nucleoside-5’-diphosphates from crude reactio...

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Bibliographic Details
Main Authors: Heidi J. Korhonen, Hannah L. Bolt, David R. W. Hodgson
Format: Article
Language:English
Published: Beilstein-Institut 2015-04-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
NDP synthesis
nucleic acids
nucleoside-5’-diphosphate
phosphorylation
Online Access:https://doi.org/10.3762/bjoc.11.52

Internet

https://doi.org/10.3762/bjoc.11.52

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