Senescent mouse cells fail to overtly regulate the HIRA histone chaperone and do not form robust Senescence Associated Heterochromatin Foci

<p>Abstract</p> <p>Background</p> <p>Cellular senescence is a permanent growth arrest that occurs in response to cellular stressors, such as telomere shortening or activation of oncogenes. Although the process of senescence growth arrest is somewhat conserved between mo...

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Bibliographic Details
Main Authors: Enders Greg H, McBryan Tony, Kennedy Alyssa L, Johnson F, Zhang Rugang, Adams Peter D
Format: Article
Language:English
Published: BMC 2010-06-01
Series:Cell Division
Online Access:http://www.celldiv.com/content/5/1/16