New Polyketides With Anti-Inflammatory Activity From the Fungus Aspergillus rugulosa

New Polyketides With Anti-Inflammatory Activity From the Fungus Aspergillus rugulosa

Two new polyketide compounds, asperulosins A and B (1–2), and one new prenylated small molecule, asperulosin C (3), along with nine known compounds (4–12), were isolated and identified from a fungus Aspergillus rugulosa. Their structures were extensively elucidated via HRESIMS, 1D, and 2D NMR analys...

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Bibliographic Details
Main Authors: Qianqian Xu, Yuben Qiao, Zijun Zhang, Yanfang Deng, Tianqi Chen, Li Tao, Qiaoxin Xu, Junjun Liu, Weiguang Sun, Ying Ye, Yuanyuan Lu, Changxing Qi, Yonghui Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Pharmacology
Subjects:
Aspergillus rugulosa
polyketides
anti-inflammatory
molecular docking
immunofluorescence
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.700573/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.700573/full

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