The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations

Due to the polyanionic nature of RNA, the principles of charge neutralization and electrostatic condensation require that cations help to overcome the repulsive forces in order for RNA to adopt a three-dimensional structure. A precise structural knowledge of RNA-metal ion interactions is crucial to...

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Bibliographic Details
Main Authors: Michelle F. Schaffer, Guanya Peng, Bernhard Spingler, Joachim Schnabl, Meitian Wang, Vincent Olieric, Roland K. O. Sigel
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:International Journal of Molecular Sciences
Subjects:
RNA
Online Access:http://www.mdpi.com/1422-0067/17/7/988