Potential Roles of the Retinoblastoma Protein in Regulating Genome Editing

Potential Roles of the Retinoblastoma Protein in Regulating Genome Editing

Genome editing is an important tool for modifying genomic DNA through introducing DNA insertion or deletion at specific locations of a genome. Recently CRISPR/Cas9 has been widely employed to improve the efficiency of genome editing. The Cas9 nuclease creates site-specific double strand breaks (DSBs...

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Bibliographic Details
Main Authors: Yuning Jiang, Wai Kit Chu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
retinoblastoma
genome editing
CRISPR/Cas9
homologous recombination
Non-Homologous End-Joining
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2018.00081/full

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https://www.frontiersin.org/article/10.3389/fcell.2018.00081/full

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