Distinct expression of the neurotoxic microRNA family let-7 in the cerebrospinal fluid of patients with Alzheimer's disease.

Distinct expression of the neurotoxic microRNA family let-7 in the cerebrospinal fluid of patients with Alzheimer's disease.

MicroRNAs (miRNAs) are non-coding RNAs originally involved in RNA silencing and post-transcriptional regulation of gene expression. We have shown in previous work that the miRNA let-7b can act as a signalling molecule for Toll-like receptor 7, thereby initiating innate immune pathways and apoptosis...

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Bibliographic Details
Main Authors: Katja Derkow, Rosa Rössling, Carola Schipke, Christina Krüger, Jakob Bauer, Michael Fähling, Andrea Stroux, Eckart Schott, Klemens Ruprecht, Oliver Peters, Seija Lehnardt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6047809?pdf=render

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http://europepmc.org/articles/PMC6047809?pdf=render

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