Seizure progression and inflammatory mediators promote pericytosis and pericyte-microglia clustering at the cerebrovasculature

Seizure progression and inflammatory mediators promote pericytosis and pericyte-microglia clustering at the cerebrovasculature

Background: Cerebrovascular dysfunction and inflammation occur in epilepsy. Here we asked whether pericytes, a pivotal cellular component of brain capillaries, undergo pathological modifications during experimental epileptogenesis and in human epilepsy. We evaluated whether pro-inflammatory cytokine...

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Bibliographic Details
Main Authors: Wendy Klement, Rita Garbelli, Emma Zub, Laura Rossini, Laura Tassi, Benoit Girard, Marine Blaquiere, Federica Bertaso, Julie Perroy, Frederic de Bock, Nicola Marchi
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Neurobiology of Disease
Subjects:
Pericytes
Blood-brain barrier
Inflammation
Microglia
Epilepsy
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118300342

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http://www.sciencedirect.com/science/article/pii/S0969996118300342

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