White matter hyperintensities across the adult lifespan: relation to age, Aβ load, and cognition

White matter hyperintensities across the adult lifespan: relation to age, Aβ load, and cognition

Abstract Background White matter hyperintensities (WMH) are very frequent in older adults and associated with worse cognitive performance. Little is known about the links between WMH and vascular risk factors, cortical β-amyloid (Aβ) load, and cognition in cognitively unimpaired adults across the en...

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Bibliographic Details
Main Authors: Antoine Garnier-Crussard, Salma Bougacha, Miranka Wirth, Claire André, Marion Delarue, Brigitte Landeau, Florence Mézenge, Elizabeth Kuhn, Julie Gonneaud, Anne Chocat, Anne Quillard, Eglantine Ferrand-Devouge, Vincent de La Sayette, Denis Vivien, Pierre Krolak-Salmon, Gaël Chételat
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Alzheimer’s Research & Therapy
Subjects:
White matter hyperintensities
Cortical Aβ
Cognition
Online Access:http://link.springer.com/article/10.1186/s13195-020-00669-4

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http://link.springer.com/article/10.1186/s13195-020-00669-4

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