Mitochondrial DNA haplogroup D4a is a marker for extreme longevity in Japan.

Mitochondrial DNA haplogroup D4a is a marker for extreme longevity in Japan.

We report results from the analysis of complete mitochondrial DNA (mtDNA) sequences from 112 Japanese semi-supercentenarians (aged above 105 years) combined with previously published data from 96 patients in each of three non-disease phenotypes: centenarians (99-105 years of age), healthy non-obese...

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Bibliographic Details
Main Authors: Erhan Bilal, Raul Rabadan, Gabriela Alexe, Noriyuki Fuku, Hitomi Ueno, Yutaka Nishigaki, Yasunori Fujita, Masafumi Ito, Yasumichi Arai, Nobuyoshi Hirose, Andrei Ruckenstein, Gyan Bhanot, Masashi Tanaka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2408726?pdf=render

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http://europepmc.org/articles/PMC2408726?pdf=render

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