Complement-Opsonized Nano-Carriers are Bound by Dendritic Cells (DC) via Complement Receptor (CR)3, and by B Cell Subpopulations via CR-1/2, and Affect the Activation of DC and B-1 Cells

Complement-Opsonized Nano-Carriers are Bound by Dendritic Cells (DC) via Complement Receptor (CR)3, and by B Cell Subpopulations via CR-1/2, and Affect the Activation of DC and B-1 Cells

The development of nanocarriers (NC) for biomedical applications has gained large interest due to their potential to co-deliver drugs in a cell-type-targeting manner. However, depending on their surface characteristics, NC accumulate serum factors, termed protein corona, which may affect their cellu...

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Bibliographic Details
Main Authors: Monika Bednarczyk, Carolina Medina-Montano, Frederic Julien Fittler, Henner Stege, Meike Roskamp, Michael Kuske, Christian Langer, Marco Vahldieck, Evelyn Montermann, Ingrid Tubbe, Nadine Röhrig, Andrzej Dzionek, Stephan Grabbe, Matthias Bros
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
nanocarrier
carbohydrate surface
complement activation
complement receptor 3
complement receptor 4
dendritic cell
Online Access:https://www.mdpi.com/1422-0067/22/6/2869

Internet

https://www.mdpi.com/1422-0067/22/6/2869

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