Pathway analysis of GWAS provides new insights into genetic susceptibility to 3 inflammatory diseases.

Although the introduction of genome-wide association studies (GWAS) have greatly increased the number of genes associated with common diseases, only a small proportion of the predicted genetic contribution has so far been elucidated. Studying the cumulative variation of polymorphisms in multiple gen...

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Bibliographic Details
Main Authors: Hariklia Eleftherohorinou, Victoria Wright, Clive Hoggart, Anna-Liisa Hartikainen, Marjo-Riitta Jarvelin, David Balding, Lachlan Coin, Michael Levin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2778995?pdf=render