AKT1 and AKT2 Promote Malignant Transformation in Human Brain Glioma LN229 Cells

AKT1 and AKT2 Promote Malignant Transformation in Human Brain Glioma LN229 Cells

OBJECTIVE To confirm the role played by AKT1 and AKT2 in the b-catenin/Tcf-4 signaling pathway in promoting malignant transfor-mation of glioma cells.METHODS LN229 cells were divided into five groups: a control group, acetone (ACE)group, acetylsalicylic acid (ASA; aspirin) group, ASA+AKT1 plasmid...

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Bibliographic Details
Main Authors: Jian Zou, Kun Wang, Lei Han, An-ling Zhang, Zhen-dong Shi, Pei-yu Pu, Chun-sheng Kang
Format: Article
Language:English
Published: China Anti-Cancer Association 2011-09-01
Series:Cancer Biology & Medicine
Subjects:
AKT1
AKT2
brain glioma
malignant transformation
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/41

Internet

http://www.cancerbiomed.org/index.php/cocr/article/view/41

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