Therapeutic Effects of Myeloid Cell Leukemia-1 siRNA on Human Acute Myeloid Leukemia Cells

Therapeutic Effects of Myeloid Cell Leukemia-1 siRNA on Human Acute Myeloid Leukemia Cells

Purpose: Up-regulation of Mcl-1, a known anti-apoptotic protein, is associated with the survival and progression of various malignancies including leukemia. The aim of this study was to explore the effect of Mcl-1 small interference RNA (siRNA) on the proliferation and apoptosis of HL-60 acute myelo...

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Bibliographic Details
Main Authors: Hadi Karami, Behzad Baradaran, Ali Esfahani, Masoud Sakhinia, Ebrahim Sakhinia
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2014-05-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Mcl-1
siRNA
Leukemia
HL-60
Apoptosis
Proliferation
Online Access:http://journals.tbzmed.ac.ir/APB/Abstract/APB_386_20131127173656

Internet

http://journals.tbzmed.ac.ir/APB/Abstract/APB_386_20131127173656

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