Actin cytoskeleton regulation of epithelial mesenchymal transition in metastatic cancer cells.

Epithelial-mesenchymal transition (EMT) is associated with loss of the cell-cell adhesion molecule E-cadherin and disruption of cell-cell junctions as well as with acquisition of migratory properties including reorganization of the actin cytoskeleton and activation of the RhoA GTPase. Here we show t...

Full description

Bibliographic Details
Main Authors: Jay Shankar, Ivan R Nabi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4355409?pdf=render