The impact of selection bias in randomized multi-arm parallel group clinical trials.

The impact of selection bias on the results of clinical trials has been analyzed extensively for trials of two treatments, yet its impact in multi-arm trials is still unknown. In this paper, we investigate selection bias in multi-arm trials by its impact on the type I error probability. We propose t...

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Bibliographic Details
Main Authors: Diane Uschner, Ralf-Dieter Hilgers, Nicole Heussen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5792025?pdf=render