Phasevarion mediated epigenetic gene regulation in Helicobacter pylori.

Many host-adapted bacterial pathogens contain DNA methyltransferases (mod genes) that are subject to phase-variable expression (high-frequency reversible ON/OFF switching of gene expression). In Haemophilus influenzae and pathogenic Neisseria, the random switching of the modA gene, associated with a...

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Bibliographic Details
Main Authors: Yogitha N Srikhanta, Rebecca J Gorrell, Jason A Steen, Jayde A Gawthorne, Terry Kwok, Sean M Grimmond, Roy M Robins-Browne, Michael P Jennings
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22162751/?tool=EBI