Inhibition of the K+ channel K(Ca)3.1 reduces TGF-β1-induced premature senescence, myofibroblast phenotype transition and proliferation of mesangial cells.

Inhibition of the K+ channel K(Ca)3.1 reduces TGF-β1-induced premature senescence, myofibroblast phenotype transition and proliferation of mesangial cells.

OBJECTIVE: K(Ca)3.1 channel participates in many important cellular functions. This study planned to investigate the potential involvement of K(Ca)3.1 channel in premature senescence, myofibroblast phenotype transition and proliferation of mesangial cells. METHODS & MATERIALS: Rat mesangial cell...

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Bibliographic Details
Main Authors: Rong-Guo Fu, Tao Zhang, Li Wang, Yan Du, Li-Ning Jia, Jing-Jing Hou, Gang-Lian Yao, Xiao-Dan Liu, Lei Zhang, Ling Chen, Bao-Song Gui, Rong-Liang Xue
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3905019?pdf=render

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http://europepmc.org/articles/PMC3905019?pdf=render

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