A new primer construction technique that effectively increases amplification of rare mutant templates in samples

Abstract Background In personalized medicine, companion diagnostic tests provide additional information to help select a treatment option likely to be optimal for a patient. Although such tests include several techniques for detecting low levels of mutant genes in wild-type backgrounds with fairly h...

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Bibliographic Details
Main Authors: Jr-Kai Huang, Ling Fan, Tao-Yeuan Wang, Pao-Shu Wu
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Biotechnology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12896-019-0555-1