Influence of mevinolin on metabolism of low density lipoproteins in primary moderate hypercholesterolemia.

Mevinolin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, was used for treatment of 12 patients with moderate hypercholesterolemia, but not classical familial hypercholesterolemia. For most patients, measurements of turnover of low density lipoprotein-apolipoprotein B (L...

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Bibliographic Details
Main Authors: S M Grundy, G L Vega
Format: Article
Language:English
Published: Elsevier 1985-12-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520342528