DNA elements for constitutive androstane receptor- and pregnane X receptor-mediated regulation of bovine CYP3A28 gene.

DNA elements for constitutive androstane receptor- and pregnane X receptor-mediated regulation of bovine CYP3A28 gene.

The regulation of cytochrome P450 3A (CYP3A) enzymes is established in humans, but molecular mechanisms of its basal and xenobiotic-mediated regulation in cattle are still unknown. Here, ~10 kbp of the bovine CYP3A28 gene promoter were cloned and sequenced, and putative transcription factor binding...

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Bibliographic Details
Main Authors: Mery Giantin, Jenni Küblbeck, Vanessa Zancanella, Viktoria Prantner, Fabiana Sansonetti, Axel Schoeniger, Roberta Tolosi, Giorgia Guerra, Silvia Da Ros, Mauro Dacasto, Paavo Honkakoski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0214338

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https://doi.org/10.1371/journal.pone.0214338

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