Monocytic MDSC mobilization promotes tumor recurrence after liver transplantation via CXCL10/TLR4/MMP14 signaling

Monocytic MDSC mobilization promotes tumor recurrence after liver transplantation via CXCL10/TLR4/MMP14 signaling

Abstract Tumor recurrence is the major obstacle for pushing the envelope of liver transplantation for hepatocellular carcinoma (HCC) patients. The inflammatory cascades activated by acute liver graft injury promote tumor recurrence. We aimed to explore the role and mechanism of myeloid-derived suppr...

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Bibliographic Details
Main Authors: Hui Liu, Chang Chun Ling, Wai Ho Oscar Yeung, Li Pang, Jiang Liu, Jie Zhou, Wei Yi Zhang, Xiao Bing Liu, Tak Pan Kevin Ng, Xin Xiang Yang, Chung Mau Lo, Kwan Man
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03788-4

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https://doi.org/10.1038/s41419-021-03788-4

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