Mutagenesis Mapping of RNA Structures within the Foot-and-Mouth Disease Virus Genome Reveals Functional Elements Localized in the Polymerase (3D <sup>pol</sup> )-Encoding Region

Mutagenesis Mapping of RNA Structures within the Foot-and-Mouth Disease Virus Genome Reveals Functional Elements Localized in the Polymerase (3D <sup>pol</sup> )-Encoding Region

Some RNA structures formed by the genomes of RNA viruses are critical for viral replication. Our study shows that of 46 conserved RNA structures located within the regions of the foot-and-mouth disease virus (FMDV) genome that encode the nonstructural proteins, only 3 are essential for replication...

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Bibliographic Details
Main Authors: Lidia Lasecka-Dykes, Fiona Tulloch, Peter Simmonds, Garry A. Luke, Paolo Ribeca, Sarah Gold, Nick J. Knowles, Caroline F. Wright, Jemma Wadsworth, Mehreen Azhar, Donald P. King, Tobias J. Tuthill, Terry Jackson, Martin D. Ryan
Format: Article
Language:English
Published: American Society for Microbiology 2021-08-01
Series:mSphere
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00015-21

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https://journals.asm.org/doi/10.1128/mSphere.00015-21

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