Affinity Purification and Comparative Biosensor Analysis of Citrulline-Peptide-Specific Antibodies in Rheumatoid Arthritis

Affinity Purification and Comparative Biosensor Analysis of Citrulline-Peptide-Specific Antibodies in Rheumatoid Arthritis

Background: In rheumatoid arthritis (RA), anti-citrullinated protein/peptide antibodies (ACPAs) are responsible for disease onset and progression, however, our knowledge is limited on ligand binding affinities of autoantibodies with different citrulline-peptide specificity. Methods: Citrulline-pepti...

Full description

Bibliographic Details
Main Authors: Eszter Szarka, Petra Aradi, Krisztina Huber, Judit Pozsgay, Lili Végh, Anna Magyar, Gergő Gyulai, György Nagy, Bernadette Rojkovich, Éva Kiss, Ferenc Hudecz, Gabriella Sármay
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:International Journal of Molecular Sciences
Subjects:
rheumatoid arthritis
citrulline-peptides
autoantibody
affinity
cross-reaction
targeting
Online Access:http://www.mdpi.com/1422-0067/19/1/326

Internet

http://www.mdpi.com/1422-0067/19/1/326

Similar Items