Concerted action of kinesins KIF5B and KIF13B promotes efficient secretory vesicle transport to microtubule plus ends

Concerted action of kinesins KIF5B and KIF13B promotes efficient secretory vesicle transport to microtubule plus ends

Intracellular transport relies on multiple kinesins, but it is poorly understood which kinesins are present on particular cargos, what their contributions are and whether they act simultaneously on the same cargo. Here, we show that Rab6-positive secretory vesicles are transported from the Golgi app...

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Bibliographic Details
Main Authors: Andrea Serra-Marques, Maud Martin, Eugene A Katrukha, Ilya Grigoriev, Cathelijn AE Peeters, Qingyang Liu, Peter Jan Hooikaas, Yao Yao, Veronika Solianova, Ihor Smal, Lotte B Pedersen, Erik Meijering, Lukas C Kapitein, Anna Akhmanova
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-11-01
Series:eLife
Subjects:
microtubule
kinesin
exocytosis
vesicle transport
Rab6
MAP7
Online Access:https://elifesciences.org/articles/61302

Internet

https://elifesciences.org/articles/61302

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