Galphimia glauca and Natural Galphimines Block Schizophrenia-Like Symptoms Induced with Apomorphine and MK-801 in Mice

Background. Galphimia glauca has been used for many years in Mexican Traditional Medicine to calm “insane people.” Triterpenes, known as galphimines, were identified in this species. One of them, Galphimine-B (G-B), acts selectively on dopaminergic neurons by antagonizing the effect of glutamate on...

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Bibliographic Details
Main Authors: Mayra Alejandra Santillán-Urquiza, Maribel Herrera-Ruiz, Alejandro Zamilpa, Enrique Jiménez-Ferrer, Rubén Román-Ramos, Elian Yuritzi Alegría-Herrera, Jaime Tortoriello
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2019/8404258