Single molecule sequencing-guided scaffolding and correction of draft assemblies

Abstract Background Although single molecule sequencing is still improving, the lengths of the generated sequences are inevitably an advantage in genome assembly. Prior work that utilizes long reads to conduct genome assembly has mostly focused on correcting sequencing errors and improving contiguit...

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Bibliographic Details
Main Authors: Shenglong Zhu, Danny Z. Chen, Scott J. Emrich
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-017-4271-8