Structure-Specific Endonucleases and the Resolution of Chromosome Underreplication

Structure-Specific Endonucleases and the Resolution of Chromosome Underreplication

Complete genome duplication in every cell cycle is fundamental for genome stability and cell survival. However, chromosome replication is frequently challenged by obstacles that impede DNA replication fork (RF) progression, which subsequently causes replication stress (RS). Cells have evolved pathwa...

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Bibliographic Details
Main Authors: Benoît Falquet, Ulrich Rass
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Genes
Subjects:
DNA replication
chromosome stability
replication stress
Holliday junction resolvase
structure-specific nuclease
ultrafine anaphase bridge
chromosome segregation
mitotic DNA synthesis
genome stability
Online Access:http://www.mdpi.com/2073-4425/10/3/232

Internet

http://www.mdpi.com/2073-4425/10/3/232

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