Antibody constant region peptides can display immunomodulatory activity through activation of the Dectin-1 signalling pathway.

Antibody constant region peptides can display immunomodulatory activity through activation of the Dectin-1 signalling pathway.

We previously reported that a synthetic peptide with sequence identical to a CDR of a mouse monoclonal antibody specific for difucosyl human blood group A exerted an immunomodulatory activity on murine macrophages. It was therapeutic against systemic candidiasis without possessing direct candidacida...

Full description

Bibliographic Details
Main Authors: Elena Gabrielli, Eva Pericolini, Elio Cenci, Claudia Monari, Walter Magliani, Tecla Ciociola, Stefania Conti, Rita Gatti, Francesco Bistoni, Luciano Polonelli, Anna Vecchiarelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3428300?pdf=render

Internet

http://europepmc.org/articles/PMC3428300?pdf=render

Similar Items