Paraoxonase-1 is not a major determinant of stent thrombosis in a Taiwanese population.

Paraoxonase-1 is not a major determinant of stent thrombosis in a Taiwanese population.

Clopidogrel is a prodrug that undergoes in vivo bioactivation to show its antiplatelet effects. Recent studies have shown that cytochrome P450 (CYP), ATP-binding cassette transporters (ABCB1), and paraoxonase-1 (PON1) play crucial roles in clopidogrel bioactivation. Here, we aim to determine the eff...

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Bibliographic Details
Main Authors: Dong-Yi Chen, Chao-Yung Wang, Ming-Shien Wen, Tsong-Hai Lee, Yen Chu, Ming-Jer Hsieh, Shang-Hung Chang, Cheng-Hung Lee, Jian-Liang Wang, Chun-Chi Chen, Laing-Suei Lu, Ming-Ta Lee, San-Jou Yeh, Fun-Chiung Lin, I-Chang Hsieh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3377663?pdf=render

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http://europepmc.org/articles/PMC3377663?pdf=render

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